span.GRAME
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Psy 8960(001) fMRI: Biological Basis and Experimental
Design
9:45-11:00 Tuesdays and
Thursdays, 203 Elliott Hall
3 credits
In contrast to the version
of this course taught Spring Õ06,
this is a true seminar course.
Student presentations will occupy the bulk of class time. The syllabus has notes on course organization, a description of
the final project and attendance and grading policies.
Logistics. The initial class will meet Tuesday,
Jan. 16, at 9:45 in 203 Elliott Hall.
Seminar courses usually meet just once a week for a long (3-hour)
session - weÕll discuss this possibility, and alternative meeting times, on the
first day of class. To respect the
schedules of all attendees, however, an unanimous vote (and room availability)
will be required to move the class away from the scheduled time and place.
|
Date |
Topic |
Potential |
|
Jan 16 |
BOLD basics |
|
|
Jan 18 |
Invention: |
Ogawa Õ93. Mini-lecture: Physics
101. |
|
Jan 23 |
Spin echo: |
Parkes Ô05 |
|
Jan 25 |
Basics: |
. Mini-Lecture: Echoes
and dephasing |
|
Jan 30 |
BOLD models: |
Buxton Õ04. Mini-Lecture: Inversion
recovery |
|
Feb 1 |
BOLD variability: |
Obata Õ05. Mini-Lecture: QUIPPS II |
|
Feb 6 |
VASO: |
Lu Õ03, Donahue Õ06. Mini-Lecture : VASO |
|
Feb 8 |
Noise: |
Triantafyllou Õ05. Mini-Lecture: SNR |
|
Feb 13 |
Neurons |
Naselaris Ô06 |
|
Feb 15 |
Oxygen consumption: |
Thompson Ô05 |
|
Feb 20 |
Local field potentials: |
Mini-Lecture: image acquisition. Logothetis Ô01 |
|
Feb 22 |
Astrocytes: |
Nedergaard Ô03 |
|
Feb 27 |
Energy budgets: |
Attwell Õ01, Lennie Ô03 |
|
Mar 1 |
Negative BOLD: |
Devor Ô05, Shmuel Ô06 |
|
Mar 6 |
Demo experiment |
Meet at CMRR |
|
Mar 8 |
Final project definitions |
5-minutes presentations
for each student, describing scope of final project, 2 primary references |
|
Mar 20 |
Linearity |
Mini-lecture: linear
systems analysis. |
|
Mar 22 |
|
Heckman Ô07 |
|
Mar 27 |
Sample data |
Meet at CMRR |
|
Mar 29 |
Analysis |
No paper assigned. Experiment
Design. http://surfer.nmr.mgh.harvard.edu/optseq/ |
|
Apr 3 |
Motion: |
Oakes Õ05; Smith Ô99 |
|
Apr 5 |
|
(analysis outside of
class) |
|
Apr 10 |
Artifacts: |
Weiskopf Ô07 |
|
Apr 12 |
|
Q&A – data
analysis on BLiSS. |
|
Apr 17 |
General linear model: |
Mini-lecture: GLM. Buxton Ch. 18 |
|
Apr 19 |
Noise and error: |
FDR - Genovese Ô02 |
|
Apr 24 |
Final Presentations |
Each student will complete
an in-depth literature review on a topic selected (and approved by the instructor)
no later than the Mar. 8 meeting. Students will spend ~30 min. presenting
their findings and submit an annotated bibliography (8 – 10
references). |
|
Apr 26 |
||
|
May 1 |
||
|
May 3 |