Psy 5065 fMRI: Hands-on Training

3:45 &ndash 4:45 pm Wednesdays, Room S204 Elliott Hall
3 &ndash 5 pm Fridays, 3T Scanner, CMRR
3 credits

Please see the syllabus for the course description and topics that will be covered.

Interesting Links

Different people have different ways of explaining MRI. Here are some that have been helpful.
   Jeff Hornak's MRI Web-book
   Brian Hargreaves' animations of spin physics
   MR-TIP, a resource for MR professionals

Please suggest the addition of any links/resources you like.

Exams

The mid-term and final exams will be take-home & open book. They should requird only pencil and paper to complete.

Date Assigned Exam Due Date
Oct 19 Midterm. Word format . pdf. Oct 26
Dec 12 Final. Word format . pdf. Dec 21

Data from the course

All data are on BLiSS (bliss.socsci.umn.edu), in /labs/olmanlab/PSY5065. Each day's data is stored there in its original format -- a "study" directory for each "subject," which contains a different DICOM directory for each scan. In most of the study directories, some of the DICOM data has been converted to Nifti format. In addition, data from a few days have been moved to topical directories (DistortionCompensation and DTI), to demonstrate pre-processing or analysis steps.

A brief guide to converting and viewing (and analyzing ... although that section is very brief) is provided here . Don't hesitate to contact the instructor if you want help moving, copying, converting or analyzing the data.

Assignments

All assignments will use one of the two functions below to simulate the scanner:
  FLASH.m
  EPI.m

   
  Date Assigned Topic Due Date
HW1 Sept 7 Basic Matlab. Instructions. Sept 14
HW2 Sept 14 FID and linewidth (Fourier transform) Sept 21
    FFT Tutorial (input data) N/A
HW3 Sept 21 Image resolution  (input data) Sept 28
HW4 Sept 28 T1 contrast  (input data) Oct 5
HW5 Oct 5 EPI vs. FLASH  (input data) Oct 19
HW6 Nov 5 Pulse sequences Blank diagrams Nov 9
HW7 Nov 16 Experiment design Nov 30
    Simulations with brain data.

Past Lectures

DateTopic
Sept 12 Introduction to NMR
Sept 19 Introduction to RF Coils
Sept 26 Gradient echo pulse sequences
Oct 3 Excitation and relaxation
Oct 10 Tracking magnetization through pulse sequences
Oct 17 Pulse sequences
Oct 24 Pulse sequences II
Oct 31 Human subjects: Screening & Safety
NIMH Workgroup Report
Nov 14 Experiment design
Nov 21 Distortion
Nov 28 Drop-out
Dec 5 Parallel imaging; course summary
Dec 12 Data from last lab: DTI, ICA & GLM

Suggested background readings

  Topic Buxton Haacke Huettel
Module 1 NMR p. 64-72, 124-135 Ch. 1, 2, 25 Ch. 1, p.49-63
  Fourier transform   Ch. 11  
  Excitation   Ch. 3, 7, 8 p. 64-72
Module 2 Gradients p. 72-81, 86-94 Ch. 27 Ch. 2
  k-space Ch. 10 Ch. 9, 10, 12 Ch. 4
Module 3 T1, T2, contrast   Ch. 4 p. 99-110
Module 4 Fast imaging p. 261-273 Ch. 19, 26 p. 120-126
Module 5 Noise p. 274-288 Ch. 15 Ch. 9
  Fieldmaps p. 288-306 Ch. 20  
Module 6 Signal loss   Ch. 20?